CSI Principal Consultant Author of Article in the Journal Environmental Toxicology and Chemistry, 2016

SETAC Env. Tox and ChemistryJeffrey Giddings, CSI Principal Consultant, is the lead author of an article published in the journal Environmental Toxicology and Chemistry, Vol. 9999, No. 9999, pp. 1-6, 2016.

The title of the article is, Synergistic effect of piperonyl butoxide (PBO) on acute toxicity of pyrethrins to Hyalella azteca.

Abstract: A series of acute toxicity tests with the amphipod Hyalella azteca was performed to quantify the synergistic effect of piperonyl butoxide (PBO) on pyrethrin toxicity. Concentrations of PBO <4 mg/L caused no toxicity enhancement, whereas toxicity increased with PBO concentrations between 4 mg/L and 15 mg/L. Additive toxicity calculations showed that true synergism accounted for an increase in pyrethrin toxicity (decrease in median lethal concentration) of 1.4-fold to 1.6-fold and varied only slightly between 4mg/L and 15 mg/L PBO, whereas direct toxicity of PBO accounted for an additional increase in mixture toxicity (up to 3.2-fold) that was proportional to PBO concentration. The results can be used to assess the risk of measured or predicted co-occurring concentrations of PBO and Pyrethrins in surface waters. Environ Toxicol Chem 2016; 9999:1–6. © 2016 SETAC

For more information or to receive a copy of the article, please contact Jeff directly (JGiddings@complianceservices.com).

Please visit our Reports and Presentations page on our website (www.complianceservices.com) or contact us at info@complianceservices.com to learn more about CSI.

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